A Pharmacokinetic Model for Amiodarone in Infants Developed from an Opportunistic Sampling Trial and Published Literature Data

Amiodarone is a first-line antiarrhythmic for life-threatening ventricular fibrillation or ventricular tachycardia in children, yet little is known about its pharmacokinetics (PK) in this population. We developed a population PK (PopPK) model using samples collected via an opportunistic study design...

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Detalhes bibliográficos
Publicado no:J Pharmacokinet Pharmacodyn
Main Authors: Dallefeld, Samantha H., Atz, Andrew M., Yogev, Ram, Sullivan, Janice E., Al-Uzri, Amira, Mendley, Susan R., Laughon, Matthew, Hornik, Christoph P., Melloni, Chiara, Harper, Barrie, Lewandowski, Andrew, Mitchell, Jeff, Wu, Huali, Green, Thomas P., Cohen-Wolkowiez, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955725/
https://ncbi.nlm.nih.gov/pubmed/29435949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-018-9576-y
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