Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents

Milrinone is a type 3 phosphodiesterase inhibitor used to improve cardiac output in critically ill infants and children. Milrinone is primarily excreted unchanged in the urine, raising concerns for toxic accumulation in the setting of renal dysfunction of critical illness. We developed a population...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Hornik, Christoph P., Yogev, Ram, Mourani, Peter M., Watt, Kevin M., Sullivan, Janice E., Atz, Andrew M., Speicher, David, Al-Uzri, Amira, Adu-Darko, Michelle, Payne, Elizabeth H., Gelber, Casey E., Lin, Susan, Harper, Barrie, Melloni, Chiara, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813877/
https://ncbi.nlm.nih.gov/pubmed/31317556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1499
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