Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents

Milrinone is a type 3 phosphodiesterase inhibitor used to improve cardiac output in critically ill infants and children. Milrinone is primarily excreted unchanged in the urine, raising concerns for toxic accumulation in the setting of renal dysfunction of critical illness. We developed a population...

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Bibliografiska uppgifter
I publikationen:J Clin Pharmacol
Huvudupphovsmän: Hornik, Christoph P., Yogev, Ram, Mourani, Peter M., Watt, Kevin M., Sullivan, Janice E., Atz, Andrew M., Speicher, David, Al-Uzri, Amira, Adu-Darko, Michelle, Payne, Elizabeth H., Gelber, Casey E., Lin, Susan, Harper, Barrie, Melloni, Chiara, Cohen-Wolkowiez, Michael, Gonzalez, Daniel
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813877/
https://ncbi.nlm.nih.gov/pubmed/31317556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1499
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