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Physiologically Based Pharmacokinetic Modeling for Trimethoprim (TMP) and Sulfamethoxazole (SMP) in Children
OBJECTIVE: We aimed to 1) determine whether opportunistically collected data can be used to develop physiologically based pharmacokinetic (PBPK) models in pediatric patients, and 2) to characterize age-related maturational changes in drug disposition for the renally eliminated and hepatically metabo...
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| Publicat a: | Clin Pharmacokinet |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6586496/ https://ncbi.nlm.nih.gov/pubmed/30840200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-00733-1 |
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