Dyrk1 inhibition improves Alzheimer's disease‐like pathology

There is an urgent need for the development of new therapeutic strategies for Alzheimer's disease (AD). The dual‐specificity tyrosine phosphorylation‐regulated kinase‐1A (Dyrk1a) is a protein kinase that phosphorylates the amyloid precursor protein (APP) and tau and thus represents a link betwe...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Branca, Caterina, Shaw, Darren M., Belfiore, Ramona, Gokhale, Vijay, Shaw, Arthur Y., Foley, Christopher, Smith, Breland, Hulme, Christopher, Dunckley, Travis, Meechoovet, Bessie, Caccamo, Antonella, Oddo, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595697/
https://ncbi.nlm.nih.gov/pubmed/28779511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12648
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