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Analysis of mRNA deadenylation by multi-protein complexes

Poly(A) tails are found at the 3′ end of almost every eukaryotic mRNA and are important for the stability of mRNAs and their translation into proteins. Thus, removal of the poly(A) tail, a process called deadenylation, is critical for regulation of gene expression. Most deadenylation enzymes are com...

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Détails bibliographiques
Publié dans:Methods
Auteurs principaux: Webster, Michael W., Stowell, James A.W., Tang, Terence T.L., Passmore, Lori A.
Format: Artigo
Langue:Inglês
Publié: Academic Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595164/
https://ncbi.nlm.nih.gov/pubmed/28624538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2017.06.009
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