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mRNA Deadenylation by Pan2/Pan3

Poly(A) tails are important regulators of mRNA stability and translational efficiency. Cytoplasmic removal of poly(A) tails by 3′-to-5′ exonucleases (deadenylation) is the rate-limiting step in mRNA degradation. Two exonuclease complexes contribute the majority of the deadenylation activity in eukar...

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Detalhes bibliográficos
Main Authors: Wolf, Jana, Passmore, Lori A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992365/
https://ncbi.nlm.nih.gov/pubmed/24450649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130211
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