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Cap-dependent deadenylation of mRNA

Poly(A) tail removal is often the initial and rate-limiting step in mRNA decay and is also responsible for translational silencing of maternal mRNAs during oocyte maturation and early development. Here we report that deadenylation in HeLa cell extracts and by a purified mammalian poly(A)-specific ex...

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Vydáno v:EMBO J
Hlavní autoři: Dehlin, Eva, Wormington, Michael, Körner, Christof G., Wahle, Elmar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10698948/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.5.1079
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