Cap-dependent deadenylation of mRNA
Poly(A) tail removal is often the initial and rate-limiting step in mRNA decay and is also responsible for translational silencing of maternal mRNAs during oocyte maturation and early development. Here we report that deadenylation in HeLa cell extracts and by a purified mammalian poly(A)-specific ex...
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| Published in: | EMBO J |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10698948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.5.1079 |
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