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Cytoplasmic deadenylation: Regulation of mRNA fate

The poly(A) tail of mRNA has an important influence on the dynamics of gene expression. On one hand, it promotes enhanced mRNA stability to allow production of the protein, even after inactivation of transcription. On the other hand, shortening of the poly(A) tail (deadenylation) slows down translat...

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Autori principali: Wiederhold, Katrin, Passmore, Lori A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890232/
https://ncbi.nlm.nih.gov/pubmed/21118121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0381531
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