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Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay.

Regulation of cytoplasmic deadenylation has a direct impact on the fate of mRNA and, consequently, its expression in the cytoplasm. AU-rich elements (AREs) found in the 3' untranslated regions of many labile mRNAs are the most common RNA-destabilizing elements known in mammalian cells. AREs direct a...

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Publicat a:Mol Cell Biol
Autors principals: Xu, N, Chen, C Y, Shyu, A B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234718/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.8.4611
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