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RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not
The Ccr4-Not complex removes mRNA poly(A) tails to regulate eukaryotic mRNA stability and translation. RNA-binding proteins contribute to specificity by interacting with both Ccr4-Not and target mRNAs, but this is not fully understood. Here, we reconstitute accelerated and selective deadenylation of...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340701/ https://ncbi.nlm.nih.gov/pubmed/30601114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40670 |
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