Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein

Polyketides are secondary metabolites which display both valuable pharmaceutical and agrochemical properties. Biosynthesis is performed by polyketide synthases (PKSs), and the acyl carrier protein (ACP), a small acidic protein, that transports the growing polyketide chain and is essential for activi...

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Veröffentlicht in:Chem Sci
Hauptverfasser: Dong, Xu, Bailey, Christopher D., Williams, Christopher, Crosby, John, Simpson, Thomas J., Willis, Christine L., Crump, Matthew P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2016
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595124/
https://ncbi.nlm.nih.gov/pubmed/28936328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03864b
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