Biosynthetic Origin of Gibberellins A(3) and A(7) in Cell-Free Preparations from Seeds of Marah macrocarpus and Malus domestica

por Albone, Kumyul S., Gaskin, Paul, MacMillan, Jake, Phinney, Bernard O., Willis, Christine L.
Publicado 1990

Stereoselective synthesis of protected l- and d-dideoxysugars and analogues via Prins cyclisations

por Beattie, Ryan J., Hornsby, Thomas W., Craig, Gemma, Galan, M. Carmen, Willis, Christine L.
Publicado en Chem Sci (2016)

Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein

por Dong, Xu, Bailey, Christopher D., Williams, Christopher, Crosby, John, Simpson, Thomas J., Willis, Christine L., Crump, Matthew P.
Publicado en Chem Sci (2016)

Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics

por Wang, Luoyi, Song, Zhongshu, Race, Paul R., Spencer, James, Simpson, Thomas J., Crump, Matthew P., Willis, Christine L.
Publicado en Chem Sci (2020)

Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives

por Alberti, Fabrizio, Khairudin, Khairunisa, Venegas, Edith Rodriguez, Davies, Jonathan A., Hayes, Patrick M., Willis, Christine L., Bailey, Andy M., Foster, Gary D.
Publicado en Nat Commun (2017)

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

por Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.
Publicado en Acta Neuropathol (2020)

Correction to: ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

por Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.
Publicado en Acta Neuropathol (2020)

Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis

por Williams, Katherine, Szwalbe, Agnieszka J., Mulholland, Nicholas P., Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Simpson, Thomas J., Cox, Russell J.
Publicado en Angew Chem Int Ed Engl (2016)

Investigations into the biosynthesis of the antifungal strobilurins

por Iqbal, Zafar, Han, Li-Chen, Soares-Sello, Anna M., Nofiani, Risa, Thormann, Gerald, Zeeck, Axel, Cox, Russell J., Willis, Christine L., Simpson, Thomas J.
Publicado en Org Biomol Chem (2018)

Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi

por Greco, Claudio, de Mattos-Shipley, Kate, Bailey, Andrew M., Mulholland, Nicholas P., Vincent, Jason L., Willis, Christine L., Cox, Russell J., Simpson, Thomas J.
Publicado en Chem Sci (2019)

Strobilurin biosynthesis in Basidiomycete fungi

por Nofiani, Risa, de Mattos-Shipley, Kate, Lebe, Karen E., Han, Li-Chen, Iqbal, Zafar, Bailey, Andrew M., Willis, Christine L., Simpson, Thomas J., Cox, Russell J.
Publicado en Nat Commun (2018)

Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi

por Szwalbe, Agnieszka J., Williams, Katherine, Song, Zhongshu, de Mattos-Shipley, Kate, Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Cox, Russell J., Simpson, Thomas J.
Publicado en Chem Sci (2018)

Novel nonadride, heptadride and maleic acid metabolites from the byssochlamic acid producer Byssochlamys fulva IMI 40021 – an insight into the biosynthesis of maleidrides

por Szwalbe, Agnieszka J., Williams, Katherine, O'Flynn, Daniel E., Bailey, Andrew M., Mulholland, Nicholas P., Vincent, Jason L., Willis, Christine L., Cox, Russell J., Simpson, Thomas J.
Publicado en Chem Commun (Camb) (2015)

Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide β-methyl branch incorporation

por Nair, Asha V., Robson, Alice, Ackrill, Thomas D., Till, Marisa, Byrne, Matthew J., Back, Catherine R., Tiwari, Kavita, Davies, Jonathan A., Willis, Christine L., Race, Paul R.
Publicado en Sci Rep (2020)

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic

por Fukuda, Daisuke, Haines, Anthony S., Song, Zhongshu, Murphy, Annabel C., Hothersall, Joanne, Stephens, Elton R., Gurney, Rachel, Cox, Russell J., Crosby, John, Willis, Christine L., Simpson, Thomas J., Thomas, Christopher M.
Publicado 2011

The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis

por de Mattos-Shipley, Kate M. J., Greco, Claudio, Heard, David M., Hough, Gemma, Mulholland, Nicholas P., Vincent, Jason L., Micklefield, Jason, Simpson, Thomas J., Willis, Christine L., Cox, Russell J., Bailey, Andrew M.
Publicado en Chem Sci (2018)

The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products

por Williams, Sam E., Stennett, Henry L., Back, Catherine R., Tiwari, Kavita, Ojeda Gomez, Jorge, Challand, Martin R., Hendry, Katharine R., Spencer, James, Essex-Lopresti, Angela E., Willis, Christine L., Curnow, Paul, Race, Paul R.
Publicado en Antibiotics (Basel) (2020)

Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics

por Thistlethwaite, Iain R. G., Bull, Freya M., Cui, Chengsen, Walker, Paul D., Gao, Shu-Shan, Wang, Luoyi, Song, Zhongshu, Masschelein, Joleen, Lavigne, Rob, Crump, Matthew P., Race, Paul R., Simpson, Thomas J., Willis, Christine L.
Publicado en Chem Sci (2017)

Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

por Bailey, Andy M., Alberti, Fabrizio, Kilaru, Sreedhar, Collins, Catherine M., de Mattos-Shipley, Kate, Hartley, Amanda J., Hayes, Patrick, Griffin, Alison, Lazarus, Colin M., Cox, Russell J., Willis, Christine L., O’Dwyer, Karen, Spence, David W., Foster, Gary D.
Publicado en Sci Rep (2016)

Uncovering biosynthetic relationships between antifungal nonadrides and octadrides

por de Mattos-Shipley, Kate M. J., Spencer, Catherine E., Greco, Claudio, Heard, David M., O'Flynn, Daniel E., Dao, Trong T., Song, Zhongshu, Mulholland, Nicholas P., Vincent, Jason L., Simpson, Thomas J., Cox, Russell J., Bailey, Andrew M., Willis, Christine L.
Publicado en Chem Sci (2020)