Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics

Kalimantacin A and batumin exhibit potent and selective antibiotic activity against Staphylococcus species including MRSA. Both compounds are formed via a hybrid polyketide synthase/non-ribosomal peptide synthetase (PKS-NRPS) biosynthetic pathway and from comparison of the gene clusters it is appare...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Thistlethwaite, Iain R. G., Bull, Freya M., Cui, Chengsen, Walker, Paul D., Gao, Shu-Shan, Wang, Luoyi, Song, Zhongshu, Masschelein, Joleen, Lavigne, Rob, Crump, Matthew P., Race, Paul R., Simpson, Thomas J., Willis, Christine L.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628338/
https://ncbi.nlm.nih.gov/pubmed/28989652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01670k
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