Identification and manipulation of the pleuromutilin gene cluster from Clitopilus passeckerianus for increased rapid antibiotic production

Semi-synthetic derivatives of the tricyclic diterpene antibiotic pleuromutilin from the basidiomycete Clitopilus passeckerianus are important in combatting bacterial infections in human and veterinary medicine. These compounds belong to the only new class of antibiotics for human applications, with...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Bailey, Andy M., Alberti, Fabrizio, Kilaru, Sreedhar, Collins, Catherine M., de Mattos-Shipley, Kate, Hartley, Amanda J., Hayes, Patrick, Griffin, Alison, Lazarus, Colin M., Cox, Russell J., Willis, Christine L., O’Dwyer, Karen, Spence, David W., Foster, Gary D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855138/
https://ncbi.nlm.nih.gov/pubmed/27143514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25202
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