ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of later life dementia, including Alzheimer’s disease (AD). The classical renin–angiotensin system (cRAS), a physiological regulator of blood pressure, functions independently within the brain and is overactive...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035243/
https://ncbi.nlm.nih.gov/pubmed/31982938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02098-6
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