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Suppression of Amyloid Deposition Leads to Long-Term Reductions in Alzheimer's Pathologies in Tg2576 Mice

In amyloid precursor protein (APP) models of amyloid deposition, the amount of amyloid deposits increase with mouse age. At a first approximation, the extent of amyloid accumulation may either reflect small excesses of production over clearance that accumulate over time or, alternatively, indicate a...

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Main Authors: Karlnoski, Rachel A., Rosenthal, Arnon, Kobayashi, Dione, Pons, Jaume, Alamed, Jennifer, Mercer, Mary, Li, Qingyou, Gordon, Marcia N., Gottschall, Paul E., Morgan, David
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688812/
https://ncbi.nlm.nih.gov/pubmed/19369565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4560-08.2009
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