Effects of Donepezil on Amyloid-β and Synapse Density in the Tg2576 Mouse Model of Alzheimer's Disease

Donepezil, an acetylcholinesterase inhibitor, is an approved drug for the treatment of Alzheimer's disease (AD). Although extensive studies have demonstrated the symptomatic efficacy of donepezil treatment in patients with AD, the effects of donepezil, if any, on the AD process are not known. I...

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Hauptverfasser: Dong, Hongxin, Yuede, Carla M., Coughlan, Carolyn A., Murphy, Keely M., Csernansky, John G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789417/
https://ncbi.nlm.nih.gov/pubmed/19799879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.09.097
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