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Effects of Memantine on Neuronal Structure and Conditioned Fear in the Tg2576 Mouse Model of Alzheimer's Disease

Memantine, an uncompetitive NMDA receptor antagonist used for the treatment of Alzheimer's disease (AD), has been hypothesized to have neuroprotective properties. However, the similarity of its mechanism of action to other NMDA receptor antagonists has led to concerns that it may also have neur...

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Detalhes bibliográficos
Main Authors: Dong, Hongxin, Yuede, Carla M, Coughlan, Carolyn, Lewis, Brian, Csernansky, John G
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664647/
https://ncbi.nlm.nih.gov/pubmed/18418360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.53
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