Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer’s disease

We examined the effects of voluntary (16 weeks of wheel running) and forced (16 weeks of treadmill running) exercise on memory-related behavior, hippocampal volume, thioflavine-stained plaque number, and soluble Aβ levels in brain tissue in the Tg2576 mouse model of Alzheimer’s disease (AD). Volunta...

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Main Authors: Yuede, Carla M., Zimmerman, Scott D., Dong, Hongxin, Kling, Matthew J., Bero, Adam W., Holtzman, David M., Timson, Benjamin F., Csernansky, John G.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745233/
https://ncbi.nlm.nih.gov/pubmed/19524672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.06.002
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