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Effects of Donepezil on Amyloid-β and Synapse Density in the Tg2576 Mouse Model of Alzheimer's Disease

Donepezil, an acetylcholinesterase inhibitor, is an approved drug for the treatment of Alzheimer's disease (AD). Although extensive studies have demonstrated the symptomatic efficacy of donepezil treatment in patients with AD, the effects of donepezil, if any, on the AD process are not known. I...

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Hlavní autoři: Dong, Hongxin, Yuede, Carla M., Coughlan, Carolyn A., Murphy, Keely M., Csernansky, John G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789417/
https://ncbi.nlm.nih.gov/pubmed/19799879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.09.097
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