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Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi

Two new dihydroxy-xanthone metabolites, agnestins A and B, were isolated from Paecilomyces variotii along with a number of related benzophenones and xanthones including monodictyphenone. The structures were elucidated by NMR analyses and X-ray crystallography. The agnestin (agn) biosynthetic gene cl...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Szwalbe, Agnieszka J., Williams, Katherine, Song, Zhongshu, de Mattos-Shipley, Kate, Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Cox, Russell J., Simpson, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335632/
https://ncbi.nlm.nih.gov/pubmed/30746079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03778g
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