Cd226(−/−) natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis in vivo

CD226 is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon binding to its ligands expressed on target cells, CD226 activates intracellular signaling that triggers cytokine production and degranulation in NK cells. However, the role of CD226 i...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Kim, Ji Sung, Shin, Bo Ram, Lee, Hong Kyung, Lee, Jae Hee, Kim, Ki Hun, Choi, Jeong Eun, Ji, A Young, Hong, Jin Tae, Kim, Youngsoo, Han, Sang-Bae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593708/
https://ncbi.nlm.nih.gov/pubmed/28920003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338994
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