Cd226(−/−) natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis in vivo

CD226 is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon binding to its ligands expressed on target cells, CD226 activates intracellular signaling that triggers cytokine production and degranulation in NK cells. However, the role of CD226 i...

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Publicat a:Oncoimmunology
Autors principals: Kim, Ji Sung, Shin, Bo Ram, Lee, Hong Kyung, Lee, Jae Hee, Kim, Ki Hun, Choi, Jeong Eun, Ji, A Young, Hong, Jin Tae, Kim, Youngsoo, Han, Sang-Bae
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593708/
https://ncbi.nlm.nih.gov/pubmed/28920003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338994
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