CCL2 deficient mesenchymal stem cells fail to establish long-lasting contact with T cells and no longer ameliorate lupus symptoms

Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disease characterized by autoantibody production. Mesenchymal stem cells (MSCs) ameliorate SLE symptoms by targeting T cells, whereas the mechanisms of their efficacy remain incompletely understood. In this study, we show that transfer o...

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Publicat a:Sci Rep
Autors principals: Lee, Hong Kyung, Kim, Hyung Sook, Kim, Ji Sung, Kim, Yong Guk, Park, Ki Hwan, Lee, Jae Hee, Kim, Ki Hun, Chang, In Young, Bae, Sang-Cheol, Kim, Youngsoo, Hong, Jin Tae, Kehrl, John H., Han, Sang-Bae
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259742/
https://ncbi.nlm.nih.gov/pubmed/28117437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41258
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