Phorbol ester activates human mesenchymal stem cells to inhibit B cells and ameliorate lupus symptoms in MRL.Fas(lpr) mice

Rationale: Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disease characterized by autoantibody production by hyper-activated B cells. Although mesenchymal stem cells (MSCs) ameliorate lupus symptoms by inhibiting T cells, whether they inhibit B cells has been controversial. Here we...

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Publicado en:Theranostics
Autores principales: Lee, Hong Kyung, Kim, Hyung Sook, Pyo, Minji, Park, Eun Jae, Jang, Sundong, Jun, Hye Won, Lee, Tae Yong, Kim, Kyung Suk, Bae, Sang-Cheol, Kim, Youngsoo, Hong, Jin Tae, Yun, Jaesuk, Han, Sang-Bae
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481409/
https://ncbi.nlm.nih.gov/pubmed/32929342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46835
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