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B Cell-Derived Interleukin 10 Does Not Regulate Spontaneous Systemic Autoimmunity in MRL.Fas(lpr) mice

B cells contribute to the pathogenesis of chronic autoimmune disorders like systemic lupus erythematosus (SLE) via multiple effector functions. However, B cells are also implicated in regulating SLE and other autoimmune syndromes via release of IL-10. B cells secreting IL-10 have been termed “Breg”...

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Detalhes bibliográficos
Main Authors: Teichmann, Lino L., Kashgarian, Michael, Weaver, Casey T., Roers, Axel, Müller, Werner, Shlomchik, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253138/
https://ncbi.nlm.nih.gov/pubmed/22156495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102456
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