Cd226(−/−) natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis in vivo

CD226 is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon binding to its ligands expressed on target cells, CD226 activates intracellular signaling that triggers cytokine production and degranulation in NK cells. However, the role of CD226 i...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Kim, Ji Sung, Shin, Bo Ram, Lee, Hong Kyung, Lee, Jae Hee, Kim, Ki Hun, Choi, Jeong Eun, Ji, A Young, Hong, Jin Tae, Kim, Youngsoo, Han, Sang-Bae
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593708/
https://ncbi.nlm.nih.gov/pubmed/28920003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338994
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