Cd226(−/−) natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis in vivo

CD226 is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon binding to its ligands expressed on target cells, CD226 activates intracellular signaling that triggers cytokine production and degranulation in NK cells. However, the role of CD226 i...

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Vydáno v:Oncoimmunology
Hlavní autoři: Kim, Ji Sung, Shin, Bo Ram, Lee, Hong Kyung, Lee, Jae Hee, Kim, Ki Hun, Choi, Jeong Eun, Ji, A Young, Hong, Jin Tae, Kim, Youngsoo, Han, Sang-Bae
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593708/
https://ncbi.nlm.nih.gov/pubmed/28920003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1338994
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