Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation

Lignende værker

• Structure-Based Optimization of Pyridoxal 5′-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis
  af: Liu, Feng, et al.
  Udgivet: (2017)
• Alternative methods for the determination of rate constants describing enzyme inactivation by an unstable inhibitor.
  af: Topham, C M
  Udgivet: (1987)
• Synthesis of a 3-Amino-2,3-dihydropyrid-4-one and Related Heterocyclic Analogs as Mechanism-Based Inhibitors of BioA, a Pyridoxal-Phosphate (PLP) Dependent Enzyme
  af: Eiden, Carter G., et al.
  Udgivet: (2017)
• Optimization of High-Throughput Sequencing Kinetics for determining enzymatic rate constants of thousands of RNA substrates
  af: Niland, Courtney N., et al.
  Udgivet: (2016)
• Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1
  af: Shah, Rachit, et al.
  Udgivet: (2016)