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Optimization of High-Throughput Sequencing Kinetics for determining enzymatic rate constants of thousands of RNA substrates

Quantification of the specificity of RNA binding proteins and RNA processing enzymes is essential to understanding their fundamental roles in biological processes. High Throughput Sequencing Kinetics (HTS-Kin) uses high throughput sequencing and internal competition kinetics to simultaneously monito...

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Detaylı Bibliyografya
Yayımlandı:Anal Biochem
Asıl Yazarlar: Niland, Courtney N., Jankowsky, Eckhard, Harris, Michael E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980219/
https://ncbi.nlm.nih.gov/pubmed/27296633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.06.004
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