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Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1

[Image: see text] Hint1 has recently emerged to be an important target of interest due to its involvement in the regulation of a broad range of CNS functions including opioid signaling, tolerance, neuropathic pain, and nicotine dependence. A series of inhibitors were rationally designed, synthesized...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Shah, Rachit, Strom, Alexander, Zhou, Andrew, Maize, Kimberly M., Finzel, Barry C., Wagner, Carston R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983727/
https://ncbi.nlm.nih.gov/pubmed/27563403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00169
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