GYY4137, a Hydrogen Sulfide Donor Modulates miR194-Dependent Collagen Realignment in Diabetic Kidney

The relationship between hydrogen sulfide (H(2)S), microRNAs (miRs), matrix metalloproteinases (MMPs) and poly-ADP-ribose-polymerase-1 (PARP-1) in diabetic kidney remodeling remains mostly obscured. We aimed at investigating whether alteration of miR-194-dependent MMPs and PARP-1 causes renal fibros...

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Bibliographic Details
Published in:Sci Rep
Main Authors: John, AM Sashi Papu, Kundu, Sourav, Pushpakumar, Sathnur, Fordham, Maura, Weber, Gregory, Mukhopadhyay, Manas, Sen, Utpal
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589897/
https://ncbi.nlm.nih.gov/pubmed/28883608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11256-3
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