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Hydrogen Sulfide Protects Hyperhomocysteinemia-Induced Renal Damage by Modulation of Caveolin and eNOS Interaction

The accumulation of homocysteine (Hcy) during chronic kidney failure (CKD) can exert toxic effects on the glomeruli and tubulo-interstitial region. Among the potential mechanisms, the formation of highly reactive metabolite, Hcy thiolactone, is known to modify proteins by N-homocysteinylation, leadi...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Pushpakumar, Sathnur, Kundu, Sourav, Sen, Utpal
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379383/
https://ncbi.nlm.nih.gov/pubmed/30778103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38467-6
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