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Exogenous hydrogen sulfide and miR-21 antagonism attenuates macrophage-mediated inflammation in ischemia reperfusion injury of the aged kidney

Ischemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) in the aging population. A reduction of hydrogen sulfide (H(2)S) production in the old kidney and renal IRI contribute to renal pathology and injury. Recent studies suggest that microRNAs (miRs) play an important role i...

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Publicat a:GeroScience
Autors principals: Pushpakumar, Sathnur, Kundu, Sourav, Weber, Gregory, Sen, Utpal
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190249/
https://ncbi.nlm.nih.gov/pubmed/33433751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00299-6
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