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MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator

Previously we reported that matrix metalloproteinase-9 (MMP-9) plays an important role in extracellular matrix (ECM) remodeling in diabetic kidney. Induction of NMDA-R and dysregulation of connexins (Cxs) were also observed. We concluded that this was due to decreased H(2)S production by down regula...

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Detalhes bibliográficos
Publicado no:Nitric Oxide
Main Authors: Kundu, Sourav, Pushpakumar, Sathnur B., Sen, Utpal
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367483/
https://ncbi.nlm.nih.gov/pubmed/25659756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2015.02.003
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