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Reovirus inhibits interferon production by sequestering IRF3 into viral factories

Upon viral infection, an arms-race between the cellular intrinsic innate immune system and viral replication is established. To win this race, viruses have established multiple strategies to inhibit the cellular response. Mammalian reovirus (MRV) constitutes a great model to study pathogenesis and l...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Stanifer, Megan L., Kischnick, Christian, Rippert, Anja, Albrecht, Dorothee, Boulant, Steeve
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589761/
https://ncbi.nlm.nih.gov/pubmed/28883463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11469-6
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