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Reovirus inhibits interferon production by sequestering IRF3 into viral factories

Upon viral infection, an arms-race between the cellular intrinsic innate immune system and viral replication is established. To win this race, viruses have established multiple strategies to inhibit the cellular response. Mammalian reovirus (MRV) constitutes a great model to study pathogenesis and l...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Stanifer, Megan L., Kischnick, Christian, Rippert, Anja, Albrecht, Dorothee, Boulant, Steeve
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589761/
https://ncbi.nlm.nih.gov/pubmed/28883463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11469-6
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