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Reovirus inhibits interferon production by sequestering IRF3 into viral factories

Upon viral infection, an arms-race between the cellular intrinsic innate immune system and viral replication is established. To win this race, viruses have established multiple strategies to inhibit the cellular response. Mammalian reovirus (MRV) constitutes a great model to study pathogenesis and l...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stanifer, Megan L., Kischnick, Christian, Rippert, Anja, Albrecht, Dorothee, Boulant, Steeve
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589761/
https://ncbi.nlm.nih.gov/pubmed/28883463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11469-6
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