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Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance

It is currently believed that type I and III interferons (IFNs) have redundant functions. However, the preferential distribution of type III IFN receptor on epithelial cells suggests functional differences at epithelial surfaces. Here, using human intestinal epithelial cells we could show that altho...

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Pubblicato in:PLoS Pathog
Autori principali: Pervolaraki, Kalliopi, Rastgou Talemi, Soheil, Albrecht, Dorothee, Bormann, Felix, Bamford, Connor, Mendoza, Juan L., Garcia, K. Christopher, McLauchlan, John, Höfer, Thomas, Stanifer, Megan L., Boulant, Steeve
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287881/
https://ncbi.nlm.nih.gov/pubmed/30485383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007420
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