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Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance

It is currently believed that type I and III interferons (IFNs) have redundant functions. However, the preferential distribution of type III IFN receptor on epithelial cells suggests functional differences at epithelial surfaces. Here, using human intestinal epithelial cells we could show that altho...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Pervolaraki, Kalliopi, Rastgou Talemi, Soheil, Albrecht, Dorothee, Bormann, Felix, Bamford, Connor, Mendoza, Juan L., Garcia, K. Christopher, McLauchlan, John, Höfer, Thomas, Stanifer, Megan L., Boulant, Steeve
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287881/
https://ncbi.nlm.nih.gov/pubmed/30485383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007420
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