Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut

Intestinal epithelial cells (IECs) are constantly exposed to commensal flora and pathogen challenges. How IECs regulate their innate immune response to maintain gut homeostasis remains unclear. Interferons (IFNs) are cytokines produced during infections. While type I IFN receptors are ubiquitously e...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pervolaraki, Kalliopi, Stanifer, Megan L., Münchau, Stephanie, Renn, Lynnsey A., Albrecht, Dorothee, Kurzhals, Stefan, Senís, Elena, Grimm, Dirk, Schröder-Braunstein, Jutta, Rabin, Ronald L., Boulant, Steeve
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399069/
https://ncbi.nlm.nih.gov/pubmed/28484457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00459
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