Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut

Intestinal epithelial cells (IECs) are constantly exposed to commensal flora and pathogen challenges. How IECs regulate their innate immune response to maintain gut homeostasis remains unclear. Interferons (IFNs) are cytokines produced during infections. While type I IFN receptors are ubiquitously e...

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書目詳細資料
發表在:Front Immunol
Main Authors: Pervolaraki, Kalliopi, Stanifer, Megan L., Münchau, Stephanie, Renn, Lynnsey A., Albrecht, Dorothee, Kurzhals, Stefan, Senís, Elena, Grimm, Dirk, Schröder-Braunstein, Jutta, Rabin, Ronald L., Boulant, Steeve
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399069/
https://ncbi.nlm.nih.gov/pubmed/28484457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00459
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