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An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells

Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus (HCV) infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV polyprotein correlate with functional single-nucle...

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Pubblicato in:J Gen Virol
Autori principali: Bamford, Connor G.G., McLauchlan, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Microbiology Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116938/
https://ncbi.nlm.nih.gov/pubmed/32897180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001495
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