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An interferon lambda 4-associated variant in the hepatitis C virus RNA polymerase affects viral replication in infected cells

Host IFNL4 haplotype status contributes to the development of chronic hepatitis C virus (HCV) infection in individuals who are acutely infected with the virus. In silico studies revealed that specific amino acid variants at multiple sites on the HCV polyprotein correlate with functional single-nucle...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gen Virol
Prif Awduron: Bamford, Connor G.G., McLauchlan, John
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Microbiology Society 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116938/
https://ncbi.nlm.nih.gov/pubmed/32897180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001495
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