Efficient Generation of Dopamine Neurons by Synthetic Transcription Factor mRNAs

Generation of functional dopamine (DA) neurons is an essential step for the development of effective cell therapy for Parkinson’s disease (PD). The generation of DA neurons can be accomplished by overexpression of DA-inducible genes using virus- or DNA-based gene delivery methods. However, these gen...

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Vydáno v:Mol Ther
Hlavní autoři: Kim, Sang-Mi, Lim, Mi-Sun, Lee, Eun-Hye, Jung, Sung Jun, Chung, Hee Yong, Kim, Chun-Hyung, Park, Chang-Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589083/
https://ncbi.nlm.nih.gov/pubmed/28705346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.06.015
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