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Efficient Generation of Dopamine Neurons by Synthetic Transcription Factor mRNAs

Generation of functional dopamine (DA) neurons is an essential step for the development of effective cell therapy for Parkinson’s disease (PD). The generation of DA neurons can be accomplished by overexpression of DA-inducible genes using virus- or DNA-based gene delivery methods. However, these gen...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Kim, Sang-Mi, Lim, Mi-Sun, Lee, Eun-Hye, Jung, Sung Jun, Chung, Hee Yong, Kim, Chun-Hyung, Park, Chang-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589083/
https://ncbi.nlm.nih.gov/pubmed/28705346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.06.015
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