Efficient Generation of Dopamine Neurons by Synthetic Transcription Factor mRNAs

Generation of functional dopamine (DA) neurons is an essential step for the development of effective cell therapy for Parkinson’s disease (PD). The generation of DA neurons can be accomplished by overexpression of DA-inducible genes using virus- or DNA-based gene delivery methods. However, these gen...

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Gepubliceerd in:Mol Ther
Hoofdauteurs: Kim, Sang-Mi, Lim, Mi-Sun, Lee, Eun-Hye, Jung, Sung Jun, Chung, Hee Yong, Kim, Chun-Hyung, Park, Chang-Hwan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589083/
https://ncbi.nlm.nih.gov/pubmed/28705346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.06.015
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