Generation of Dopamine Neurons from Rodent Fibroblasts through the Expandable Neural Precursor Cell Stage

Recent groundbreaking work has demonstrated that combined expression of the transcription factors Brn2, Ascl1, and Myt1L (BAM; also known as Wernig factors) convert mouse fibroblasts into postmitotic neuronal cells. However, questions remain regarding whether trans-conversion is achieved directly or...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lim, Mi-Sun, Chang, Mi-Yoon, Kim, Sang-Mi, Yi, Sang-Hoon, Suh-Kim, Haeyoung, Jung, Sung Jun, Kim, Min Jung, Kim, Jin Hyuk, Lee, Yong-Sung, Lee, Soo Young, Kim, Dong-Wook, Lee, Sang-Hun, Park, Chang-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498077/
https://ncbi.nlm.nih.gov/pubmed/26023233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629808
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