Generation of Dopamine Neurons from Rodent Fibroblasts through the Expandable Neural Precursor Cell Stage

Recent groundbreaking work has demonstrated that combined expression of the transcription factors Brn2, Ascl1, and Myt1L (BAM; also known as Wernig factors) convert mouse fibroblasts into postmitotic neuronal cells. However, questions remain regarding whether trans-conversion is achieved directly or...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Lim, Mi-Sun, Chang, Mi-Yoon, Kim, Sang-Mi, Yi, Sang-Hoon, Suh-Kim, Haeyoung, Jung, Sung Jun, Kim, Min Jung, Kim, Jin Hyuk, Lee, Yong-Sung, Lee, Soo Young, Kim, Dong-Wook, Lee, Sang-Hun, Park, Chang-Hwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498077/
https://ncbi.nlm.nih.gov/pubmed/26023233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629808
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