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Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma
CIC (also known as Capicua) is a transcriptional repressor negatively regulated by RAS/MAPK signaling. Whereas the functions of Cic have been well characterized in Drosophila, little is known about its role in mammals. CIC is inactivated in a variety of human tumors and has been implicated recently...
Enregistré dans:
| Publié dans: | Genes Dev |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588927/ https://ncbi.nlm.nih.gov/pubmed/28827401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.300244.117 |
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