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The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer
The transcriptional repressor Capicua (CIC) has emerged as an important rheostat of cell growth regulated by RAS/MAPK signaling. Cic was originally discovered in Drosophila, where it was shown to be inactivated by MAPK signaling downstream of the RTKs Torso and EGFR, which results in signal-dependen...
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| Publicado en: | Cell Cycle |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5969551/ https://ncbi.nlm.nih.gov/pubmed/29578365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1450029 |
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